Overview
The FDA briefing discusses a seven-residue thymosin β4 fragment under the name TB-500 and notes that this common name has also been used for different salts or derivatives. The fragment should be distinguished from full-length thymosin β4.
Identity & classification
- NAME
- TB-500
- RESEARCH CATEGORY
- TISSUE-REPAIR RESEARCH
- MOLECULAR CLASS
- N-terminally acetylated seven-residue fragment
- KEY DISTINCTION
- Do not conflate the fragment, full-length molecule or salt forms
Reading the evidence
Before comparing mass or analytical results, establish the sequence, terminal modifications and chemical form. Records using the same short name but different identity descriptions need to be checked against their original documents.